Session : Organ Protection during CPB Topic : Preventing Acute Kidney Injury after Cardiac Surgery
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چکیده
منابع مشابه
Correlation of intraoperative renal near infrared spectroscopy with the development of acute kidney injury in adult patients undergoing cardiac surgery using cardiopulmonary bypass
Introduction: The present study aimed to correlate renal oximetry near-infrared spectroscopy (NIRS) values with conventional non-invasive biomarkers for the early detection of acute kidney injury (AKI) in adult patients undergoing cardiac surgery using cardiopulmonary bypass (CPB). Accordingly, renal NIRS can be employed as a trending device for the prevention of AKI developmen...
متن کاملCystatin C and neutrophil gelatinase-associated lipocalin (NGAL) as novel biomarkers for monitoring acute kidney injury after cardiac surgery
Background Acute kidney injury (AKI) occurs frequently after cardiac surgery using cardiopulmonary bypass (CPB). Conventional markers of kidney function like creatinine and potassium concentration are unreliable indicators during acute changes in kidney function and demonstrate injury late in the clinical course. Therefore, in the search of more sensitive biomarkers for monitoring AKI following...
متن کاملDuration of cardiopulmonary bypass is an important confounder when using biomarkers for early diagnosis of acute kidney injury in cardiac surgical patients
Objectives: Acute kidney injury is an important complication in patients undergoing cardiac surgery. Recently, several biomarkers to facilitate early detection of acute kidney injury have been proposed, among them Neutrophil-gelatinase-associated-lipocalin, Kidney-injury-molecule-1, and LFatty-acid-binding-protein. The expression of these markers is increased by ischemia-reperfusion injury and ...
متن کاملAcute Kidney Injury Subsequent to Cardiac Surgery.
Acute kidney injury (AKI) after cardiac surgery is a common and underappreciated syndrome that is associated with poor shortand long-term outcomes. AKI after cardiac surgery may be epiphenomenon, a signal for adverse outcomes by virtue of other affected organ systems, and a consequence of multiple factors. Subtle increases in serum creatinine (SCr) postoperatively, once considered inconsequenti...
متن کاملNovel biomarkers, oxidative stress, and the role of labile iron toxicity in cardiopulmonary bypass-associated acute kidney injury.
Cardiac surgery-associated acute kidney injury (AKI) is common and carries a poor prognosis. Hemodynamic and inflammatory factors and the release of labile iron, contributing to oxidation from reactive oxygen species are among the major determinants of cardiac surgery-associated AKI. The diagnosis of AKI is typically delayed because of the limitations of currently used clinical biomarkers indic...
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